Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944488 | 0.79 | KCNH2 (0.37) | MEN1KMT2AHSD17B10KCNH2PDE10A | |
| SCHEMBL19863981 | 0.75 | KCNH2 (0.35) | MEN1KMT2AHSD17B10KCNH2PDE10A | |
| SCHEMBL7981590 | 0.73 | PDE8B (0.35) | MEN1KMT2AHSD17B10KCNH2PDE10A | |
| SCHEMBL26774843 | 0.73 | HDAC6 (0.36) | MEN1KMT2AHSD17B10KCNH2PDE10A | |
| SCHEMBL26725551 | 0.72 | CSF1R (0.34) | MEN1KMT2AHSD17B10KCNH2PDE10A | |
| SCHEMBL14860590 | 0.72 | MEN1 (0.40) | MEN1KMT2AHSD17B10KCNH2PDE10A | |
| SCHEMBL23773625 | 0.71 | DUT (0.37) | MEN1KMT2AHSD17B10KCNH2PDE10A | |
| SCHEMBL20976274 | 0.69 | HDAC6 (0.41) | MEN1KMT2AHSD17B10KCNH2PDE10A | |
| SCHEMBL8342570 | 0.69 | — | — | |
| SCHEMBL1751510 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589630-B1 | CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME | ASSEMBLY BIOSCIENCES INC (US) | 2021-07-07 | — | — | EP | disclosed |