Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 9/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.31 |
| ▸ | WNT1 | P04628 | 6/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23617616 | 0.81 | IDO1 (0.32) | IDO1GSK3BDYRK1AWNT1GPR119 | |
| SCHEMBL23617550 | 0.81 | — | — | |
| SCHEMBL23617491 | 0.81 | AKT1 (0.38) | — | |
| SCHEMBL23617851 | 0.79 | GSK3B (0.32) | IDO1GSK3BDYRK1AWNT1 | |
| SCHEMBL23617852 | 0.79 | GSK3B (0.32) | IDO1GSK3BDYRK1AWNT1 | |
| SCHEMBL23617834 | 0.78 | — | — | |
| SCHEMBL22023364 | 0.77 | DYRK1A (0.37) | DYRK1APRMT5WDR77 | |
| SCHEMBL23617596 | 0.76 | KDM4E (0.34) | — | |
| SCHEMBL23617849 | 0.76 | — | — | |
| SCHEMBL23617667 | 0.75 | SYK (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589630-B1 | CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME | ASSEMBLY BIOSCIENCES INC (US) | 2021-07-07 | — | — | EP | disclosed |