Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23617463 | 0.79 | ALDH1A1 (0.38) | KDM4EMEN1ALDH1A1THRBKMT2A | |
| SCHEMBL23617849 | 0.78 | — | — | |
| SCHEMBL23617550 | 0.78 | — | — | |
| SCHEMBL23617834 | 0.77 | — | — | |
| SCHEMBL23617853 | 0.76 | IDO1 (0.35) | — | |
| SCHEMBL23617491 | 0.76 | AKT1 (0.38) | — | |
| SCHEMBL23617255 | 0.74 | MAPT (0.35) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL23617464 | 0.72 | ALDH1A1 (0.44) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL22023364 | 0.72 | DYRK1A (0.37) | — | |
| SCHEMBL12539165 | 0.70 | PLG (0.41) | KDM4EMEN1ALDH1A1THRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589630-B1 | CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME | ASSEMBLY BIOSCIENCES INC (US) | 2021-07-07 | — | — | EP | disclosed |