SCHEMBL23617866

SCHEMBL23617866

COC(O)c1cnn(C)n1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6736342 0.72
SCHEMBL12909323 0.68 KEAP1 (0.37)
SCHEMBL12970372 0.65
SCHEMBL25883207 0.64 IDO1 (0.35)
SCHEMBL12049663 0.63
SCHEMBL24900384 0.62 PI4KA (0.30)
SCHEMBL23340115 0.61
SCHEMBL17067240 0.60 CCR1 (0.41)
SCHEMBL15360300 0.60 ADORA2A (0.33)
SCHEMBL864815 0.60 MAPK1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3558988-B1 PYRAZOLO[3,4-B]PYRIDINES AND IMIDAZO[1,5-B]PYRIDAZINES AS PDE1 INHIBITORS H LUNDBECK AS (DK) 2021-07-07 EP disclosed