Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15704165 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL23450964 | 0.77 | — | — | |
| SCHEMBL20227100 | 0.76 | USP2 (0.38) | — | |
| SCHEMBL9394354 | 0.75 | TSHR (0.43) | TSHR | |
| SCHEMBL15856892 | 0.75 | — | — | |
| SCHEMBL15358596 | 0.73 | TSHR (0.41) | TSHR | |
| SCHEMBL4537870 | 0.72 | GAA (0.35) | — | |
| SCHEMBL7357628 | 0.71 | — | — | |
| SCHEMBL8538942 | 0.69 | ALDH1A1 (0.30) | TSHR | |
| SCHEMBL2684043 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350177-B1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-07-07 | — | — | EP | disclosed |