SCHEMBL23618045

SCHEMBL23618045

CCC1CCC(c2ccc(C#Cc3ccc(OC)c(F)c3F)cc2)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACACB O00763 3/20 0.33
AR P10275 2/20 0.33
AAK1 Q2M2I8 1/20 0.33
PAX8 Q06710 5/20 0.32
CCR5 P51681 1/20 0.31
DRD2 P14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9512315 1.00 ACACB (0.33) ACACBARAAK1PAX8CCR5
SCHEMBL9509449 0.91 CYP2C9 (0.41) ACACBARAAK1PAX8CCR5
SCHEMBL9509015 0.91 ACACB (0.38) ACACB
SCHEMBL9512392 0.89 CYP2C9 (0.34) ACACBARPAX8DRD2
SCHEMBL9510192 0.88 CYP2C9 (0.34) ACACBARPAX8DRD2
SCHEMBL9512338 0.87 ACACB (0.34) ACACB
SCHEMBL9509344 0.87 SPHK1 (0.34)
SCHEMBL9511371 0.87 SPHK1 (0.34)
SCHEMBL9512291 0.86 ESR2 (0.39) AAK1PAX8
SCHEMBL12230852 0.86 ESR2 (0.39) AAK1PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021134883-A1 LIQUID CRYSTAL COMPOSITION OF NEGATIVE LIQUID CRYSTAL COMPOUND HAVING METHOXY BRIDGE BOND AND USE THEREOF 北京八亿时空液晶科技股份有限公司 2021-07-08 WO disclosed