Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614465 | 1.00 | RORC (0.44) | RORCNR1H3NR1H2MAPTPDE2A | |
| SCHEMBL23611036 | 0.93 | NR1H3 (0.40) | RORCNR1H3NR1H2MAPT | |
| SCHEMBL23611035 | 0.93 | NR1H3 (0.40) | RORCNR1H3NR1H2MAPT | |
| SCHEMBL23619089 | 0.90 | RORC (0.42) | RORCPDE2A | |
| SCHEMBL28615097 | 0.90 | RORC (0.42) | RORCPDE2A | |
| SCHEMBL28634003 | 0.90 | RORC (0.42) | RORCPDE2ASCN9A | |
| SCHEMBL28618421 | 0.90 | IDO1 (0.42) | RORCPDE2ASCN9A | |
| SCHEMBL23618980 | 0.90 | RORC (0.42) | RORCPDE2ASCN9A | |
| SCHEMBL23619020 | 0.90 | IDO1 (0.42) | RORCPDE2ASCN9A | |
| SCHEMBL23619011 | 0.88 | RORC (0.49) | RORCPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |
| WO-2021136339-A1 | AMIDE COMPOUND WITH BICYCLIC STRUCTURE AND USE THEREOF IN DRUG | 广东东阳光药业有限公司 | 2021-07-08 | — | — | WO | disclosed |