SCHEMBL236191

SCHEMBL236191

COc1ccccc1OC(C)=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA4 P22748 1/20 0.59
CA7 P43166 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59
TSHR P16473 2/20 0.59
KDM4E B2RXH2 2/20 0.59
HSD17B10 Q99714 2/20 0.59
ALDH1A1 P00352 2/20 0.59
PTGS1 P23219 2/20 0.59
ESR1 P03372 1/20 0.59
ITGB3 P05106 1/20 0.59
ITGA2B P08514 1/20 0.59
HMGB1 P09429 1/20 0.59
HPGD P15428 1/20 0.59
GGT1 P19440 1/20 0.59
PTGS2 P35354 1/20 0.59
BLM P54132 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29655351 1.00 CA12 (0.59) CA12CA1CA2CA4CA7
SCHEMBL338196 0.91 PTGS2 (0.68) TSHRKDM4EHSD17B10ALDH1A1PTGS1
SCHEMBL29432883 0.91 PTGS2 (0.68) TSHRKDM4EHSD17B10ALDH1A1PTGS1
Iodide SCHEMBL30619798 0.88 PTGS2 (0.65) TSHRKDM4EHSD17B10ALDH1A1PTGS1
Guacetisal SCHEMBL29368893 0.87 KDM4E (0.73) TSHRKDM4EHSD17B10ALDH1A1PTGS1
Guacetisal SCHEMBL948974 0.87 KDM4E (0.73) TSHRKDM4EHSD17B10ALDH1A1PTGS1
Ethylene SCHEMBL28225928 0.86 PTGS2 (0.63) TSHRKDM4EHSD17B10ALDH1A1PTGS1
1,2-Dimethoxybenzene SCHEMBL28254681 0.86 CA1 (0.65) CA12CA1CA2CA4CA7
1,2-Dimethoxybenzene SCHEMBL27898360 0.85 CA1 (0.72) CA12CA1CA2CA4CA7
SCHEMBL16236644 0.85 KDM4E (0.53) CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025058459-A1 NOVEL IMIDAZOPYRIDINE-BASED COMPOUND AND COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING, ALLEVIATING, OR TREATING GASTROINTESTINAL INFLAMMATORY DISEASES OR GASTRIC ACID-RELATED DISEASES (주)휴온스 2025-03-20 WO claimed
CN-119490612-A Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2025-02-21 CN claimed
CN-119490410-A Ether ester compound, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2025-02-21 CN claimed
CN-115932107-B Method for detecting impurity content in vanillyl ethanone sample 盐城师范学院 2025-02-21 CN claimed
CN-112694426-B Synthetic method of apremilast intermediate 山东铂源药业股份有限公司 2022-11-04 CN claimed
CN-115252814-A Cyclodextrin-metal organic framework composition and preparation method thereof 中国科学院上海药物研究所 2022-11-01 CN claimed
CN-113197204-A Preparation method of plant growth regulating compound sodium nitrophenolate 何志松 2021-08-03 CN claimed
EP-3809876-A1 PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME PERPRIN S.R.L. (IT) 2021-04-28 EP claimed
CN-112694426-A Synthetic method of apremilast intermediate 山东铂源药业有限公司 2021-04-23 CN claimed
CN-111333515-A Method for producing 5-nitroguaiacol sodium by using microchannel reaction device 郑州郑氏化工产品有限公司 2020-06-26 CN claimed
WO-2005066187-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO claimed
WO-2005066186-A2 CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO claimed
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
US-20050136021-A1 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
WO-2004041544-A1 HETERO-SUBSTITUTED ARYL ACETIC ACID CO-INITIATORS FOR IR-SENSITIVE COMPOSITIONS KODAK POLYCHROME GRAPHICS LLC (US) 2004-05-21 WO claimed
US-20040091811-A1 Hetero-substituted aryl acetic acid co-initiators for IR-sensitive compositions KODAK POLYCHROME GRAPHICS, LLC 2004-05-13 US claimed
EP-0591861-B1 Reactivity control in microcrystalline coupler dispersions EASTMAN KODAK CO (US) 1999-07-28 EP claimed
US-5434036-A Process for forming microcrystalline coupler dispersions EASTMAN KODAK COMPANY (US) 1995-07-18 US claimed
US-5401623-A Color photography EASTMAN KODAK COMPANY (US) 1995-03-28 US claimed
EP-0591861-A1 Reactivity control in microcrystalline coupler dispersions EASTMAN KODAK COMPANY (US) 1994-04-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients F9, RPL39, ECPAS CA12 2980/4885CA1 2172/4885CA2 3862/4885
US-20050136021-A1 Active-releasing cyclic siloxanes F9, RPL39, ALDH16A1 CA12 2608/4885CA1 1581/4885CA2 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.