Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 6/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25812470 | 0.92 | NT5E (0.44) | NT5EADORA1RNASELIMPDH2DNPH1 | |
| SCHEMBL23619370 | 0.92 | NT5E (0.44) | NT5EADORA1RNASELIMPDH2DNPH1 | |
| SCHEMBL23619399 | 0.90 | P2RY1 (0.52) | ADORA1RNASELDNPH1PRKAB2TRPM2 | |
| SCHEMBL23619339 | 0.90 | NT5E (0.43) | NT5EADORA1RNASELIMPDH2DNPH1 | |
| SCHEMBL23619226 | 0.89 | ADORA1 (0.54) | NT5EADORA1RNASEL | |
| SCHEMBL23619484 | 0.88 | NT5E (0.44) | NT5EADORA1IMPDH2DNPH1PRKAB2 | |
| SCHEMBL24499687 | 0.87 | STING1 (0.51) | NT5EADORA1RNASELTAS1R3TAS1R1 | |
| SCHEMBL18511001 | 0.87 | STING1 (0.51) | NT5EADORA1RNASELTAS1R3TAS1R1 | |
| SCHEMBL18510995 | 0.87 | STING1 (0.51) | NT5EADORA1RNASELTAS1R3TAS1R1 | |
| SCHEMBL23619346 | 0.85 | ADORA1 (0.46) | NT5EADORA1RNASELIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | MERCK SHARP & DOHME LLC (US) | 2023-06-27 | — | — | US | disclosed |
| US-20210206796-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206796-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | STING1, CGAS, IFNAR1 | NT5E 1544/4885ADORA1 34/4885RNASEL 547/4885 |
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | STING1, CGAS, IFNAR1 | NT5E 1586/4885ADORA1 33/4885RNASEL 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.