Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.44 |
| ▸ | FHIT | P49789 | 5/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619323 | 0.88 | NT5E (0.45) | NT5EP2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL25812470 | 0.88 | NT5E (0.44) | NT5EFHITP2RY1P2RY2SRC | |
| SCHEMBL23619370 | 0.88 | NT5E (0.44) | NT5EFHITP2RY1P2RY2SRC | |
| SCHEMBL23619339 | 0.87 | NT5E (0.43) | NT5EFHITP2RY1P2RY2SRC | |
| SCHEMBL23619226 | 0.81 | ADORA1 (0.54) | NT5EADORA1 | |
| SCHEMBL18521236 | 0.80 | NT5E (0.48) | NT5ETAS1R3TAS1R1P2RX3 | |
| SCHEMBL18520893 | 0.80 | NT5E (0.48) | NT5ETAS1R3TAS1R1P2RX3 | |
| SCHEMBL18522064 | 0.80 | NT5E (0.48) | NT5ETAS1R3TAS1R1P2RX3 | |
| SCHEMBL25812398 | 0.80 | ADORA1 (0.36) | NT5EP2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL24236877 | 0.79 | NT5E (0.55) | NT5EFHITP2RY1P2RY2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206796-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206796-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | STING1, CGAS, IFNAR1 | NT5E 1544/4885FHIT 4585/4885P2RY1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.