SCHEMBL23619640

SCHEMBL23619640

CN(C)CC(=O)Nc1cccc2c1CCNC2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
LMNA P02545 4/20 0.46
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2D6 P10635 1/20 0.46
PARP14 Q460N5 1/20 0.43
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.43
CD44 P16070 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HPGD P15428 2/20 0.38
ATM Q13315 1/20 0.38
P2RX7 Q99572 1/20 0.38
P2RY1 P47900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27372303 0.85 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ALMNATHRA
SCHEMBL29865634 0.82 KDM4E (0.51) ALDH1A1MEN1KMT2ALMNATHRA
SCHEMBL1011302 0.81 NPC1 (0.52) ALDH1A1MEN1KMT2ALMNATHRA
SCHEMBL21744604 0.80 CD44 (0.40) ALDH1A1MEN1KMT2ALMNAPOLB
SCHEMBL14863130 0.79 CD44 (0.46) ALDH1A1MEN1KMT2ALMNATHRA
SCHEMBL11738897 0.76 TSHR (0.45) ALDH1A1MEN1KMT2ALMNATHRA
SCHEMBL29866041 0.75 CD44 (0.43) KDM4ECD44
SCHEMBL21743774 0.75 MEN1 (0.55) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL21743777 0.75 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ALMNATHRA
SCHEMBL16268278 0.75 CD44 (0.45) ALDH1A1MEN1KMT2ALMNATHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066417-B Factor XIa inhibitors 上海京新生物医药有限公司 2025-05-02 CN disclosed
CN-115066417-A Factor XIa inhibitors 上海京新生物医药有限公司 2022-09-16 CN disclosed
WO-2021136390-A1 BLOOD COAGULATION FACTOR XIA INHIBITOR 上海京新生物医药有限公司 2021-07-08 WO disclosed
WO-2021136390-A1 BLOOD COAGULATION FACTOR XIA INHIBITOR 上海京新生物医药有限公司 2021-07-08 WO disclosed