Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 8/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 8/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.40 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620013 | 0.98 | P2RX4 (0.51) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23619947 | 0.96 | P2RX4 (0.47) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23619852 | 0.91 | ANO1 (0.43) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23619991 | 0.88 | ANO1 (0.42) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23620005 | 0.87 | P2RX4 (0.49) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23619891 | 0.86 | P2RX4 (0.63) | P2RX4 | |
| SCHEMBL30812821 | 0.86 | P2RX4 (0.63) | P2RX4 | |
| SCHEMBL23619949 | 0.86 | ANO1 (0.47) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23620009 | 0.85 | ANO1 (0.45) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL24714040 | 0.85 | RORA (0.44) | P2RX4ANO1KCNJ5KCNJ3RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |