Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696554 | 0.98 | SIGMAR1 (0.49) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| SCHEMBL30380947 | 0.98 | SIGMAR1 (0.49) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| SCHEMBL30799092 | 0.98 | SIGMAR1 (0.51) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| SCHEMBL29906514 | 0.98 | SIGMAR1 (0.51) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| SCHEMBL272955 | 0.98 | SIGMAR1 (0.51) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| SCHEMBL292397 | 0.98 | SIGMAR1 (0.51) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| SCHEMBL13250571 | 0.96 | SIGMAR1 (0.47) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| SCHEMBL4893902 | 0.96 | SIGMAR1 (0.50) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| SCHEMBL4580501 | 0.96 | SIGMAR1 (0.50) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 | |
| Water SCHEMBL10786412 | 0.96 | SIGMAR1 (0.50) | SIGMAR1L3MBTL1ALDH1A1CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361444-A1 | MATERIALS | Lomox Limited (GB) | 2011-08-31 | — | — | EP | disclosed |
| WO-2009103952-A1 | MATERIALS | LOMOX LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |