Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619975 | 0.86 | ANO1 (0.36) | KMT2AP2RX4ALDH1A1 | |
| SCHEMBL23619719 | 0.86 | ANO1 (0.44) | LMNAP2RX4POLBALDH1A1 | |
| SCHEMBL23619859 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRKMT2ANPSR1MAPT | |
| SCHEMBL29162299 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRKMT2ANPSR1MAPT | |
| SCHEMBL23619935 | 0.79 | ANO1 (0.44) | LMNAP2RX4POLBALDH1A1 | |
| SCHEMBL24714003 | 0.76 | ATR (0.42) | ALDH1A1 | |
| SCHEMBL23620027 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRKMT2ANPSR1MAPT | |
| SCHEMBL23620002 | 0.76 | KCNJ5 (0.39) | SMN1; SMN2MAPTLMNAP2RX4POLB | |
| SCHEMBL24713240 | 0.73 | NR2E1 (0.39) | KMT2ANPSR1LMNAP2RX4POLB | |
| SCHEMBL29162300 | 0.69 | ANO1 (0.37) | KMT2AMAPTLMNAP2RX4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |