Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619719 | 0.88 | ANO1 (0.44) | ANO1ALDH1A1P2RX4RORANR2E1 | |
| SCHEMBL23620162 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1P2RX4KMT2A | |
| SCHEMBL23619974 | 0.82 | ANO1 (0.37) | ANO1ALDH1A1P2RX4KMT2ARECQL | |
| SCHEMBL29162300 | 0.82 | ANO1 (0.37) | ANO1ALDH1A1P2RX4KMT2ARECQL | |
| SCHEMBL23619935 | 0.80 | ANO1 (0.44) | ANO1ALDH1A1P2RX4RORANR2E1 | |
| SCHEMBL24714003 | 0.77 | ATR (0.42) | ALDH1A1EGFR | |
| SCHEMBL23620002 | 0.77 | KCNJ5 (0.39) | ANO1ALDH1A1P2RX4RORANR2E1 | |
| SCHEMBL23620016 | 0.76 | ALDH1A1 (0.39) | ANO1ALDH1A1EGFRERBB2RORA | |
| SCHEMBL23620035 | 0.75 | RECQL (0.39) | ANO1ALDH1A1EGFRERBB2RORA | |
| SCHEMBL23619987 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |