Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.45 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620020 | 0.91 | KCNJ5 (0.53) | ANO1KCNJ5KCNJ3NR2E1RORA | |
| SCHEMBL23619970 | 0.90 | ANO1 (0.44) | ANO1KCNJ5KCNJ3NR2E1RORA | |
| SCHEMBL23619949 | 0.90 | ANO1 (0.47) | ANO1KCNJ5KCNJ3NR2E1RORA | |
| SCHEMBL23620187 | 0.89 | ANO1 (0.43) | ANO1KCNJ5KCNJ3NR2E1RORA | |
| SCHEMBL24714040 | 0.87 | RORA (0.44) | ANO1KCNJ5KCNJ3NR2E1RORA | |
| SCHEMBL23619738 | 0.86 | KCNJ5 (0.48) | ANO1KCNJ5KCNJ3NR2E1RORA | |
| SCHEMBL23620012 | 0.86 | ANO1 (0.47) | ANO1KCNJ5KCNJ3NR2E1RORA | |
| SCHEMBL23620015 | 0.85 | MAPK8 (0.49) | ANO1NR2E1RORAP2RX4MAPK8 | |
| SCHEMBL23620189 | 0.85 | NR2E1 (0.49) | ANO1KCNJ5KCNJ3NR2E1RORA | |
| SCHEMBL23619947 | 0.85 | P2RX4 (0.47) | ANO1KCNJ5KCNJ3NR2E1RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |