Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620493 | 0.83 | SYK (0.46) | GAA | |
| SCHEMBL30479295 | 0.83 | SYK (0.46) | GAA | |
| SCHEMBL31465472 | 0.80 | IRAK4 (0.32) | HTTXPO1 | |
| SCHEMBL23948498 | 0.79 | JUN (0.30) | — | |
| SCHEMBL31612044 | 0.78 | MAPK8 (0.46) | HTTXPO1 | |
| SCHEMBL23618686 | 0.72 | GSK3A (0.37) | XPO1 | |
| SCHEMBL23625331 | 0.71 | KMT2A (0.39) | — | |
| SCHEMBL23625491 | 0.71 | MAPK8 (0.34) | HTT | |
| SCHEMBL20330481 | 0.70 | MAPK8 (0.37) | HTTXPO1 | |
| SCHEMBL23618826 | 0.70 | EPHX2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121538-B | Furan derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| WO-2021136461-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | 成都百裕制药股份有限公司 | 2021-07-08 | — | — | WO | disclosed |
| WO-2021136462-A1 | FURAN DERIVATIVES AND APPLICATION THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2021-07-08 | — | — | WO | disclosed |