Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23622256 | 0.91 | NR3C1 (0.48) | NR3C1PGRROCK2 | |
| SCHEMBL23622250 | 0.91 | NR3C1 (0.57) | NR3C1TNFPGR | |
| SCHEMBL23622154 | 0.89 | NR3C1 (0.55) | NR3C1TNFPGR | |
| SCHEMBL23622255 | 0.89 | NR3C1 (0.43) | NR3C1TNFROCK2 | |
| SCHEMBL23622254 | 0.87 | NPC1 (0.42) | NR3C1ROCK2 | |
| SCHEMBL23619039 | 0.82 | NR3C1 (0.42) | NR3C1TNFPGR | |
| SCHEMBL17644001 | 0.80 | NR3C1 (0.61) | NR3C1TNFPGR | |
| SCHEMBL19459958 | 0.80 | NR3C1 (0.61) | NR3C1TNFPGR | |
| SCHEMBL23622397 | 0.79 | NR3C1 (0.44) | NR3C1TNFPGRROCK2 | |
| SCHEMBL21182244 | 0.78 | NR3C1 (0.43) | NR3C1TNFPGRROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167068-A1 | BENZOPYRAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-20230167068-A1 | BENZOPYRAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-06-01 | — | — | US | disclosed |
| WO-2021136429-A1 | BENZOPYRAZOLE COMPOUND | 南京明德新药研发有限公司 | 2021-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167068-A1 | BENZOPYRAZOLE COMPOUND | ABCB1, CYP3A43, CYP3A5 | NR3C1 3472/4885TNF 4841/4885PGR 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.