Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.80 |
| ▸ | PGR | P06401 | 2/20 | 0.69 |
| ▸ | TNF | P01375 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23622244 | 0.93 | NR3C1 (0.81) | NR3C1PGRTNF | |
| SCHEMBL23622238 | 0.91 | NR3C1 (0.74) | NR3C1PGRTNF | |
| SCHEMBL23622125 | 0.91 | NR3C1 (0.70) | NR3C1PGRTNF | |
| SCHEMBL26158280 | 0.90 | NR3C1 (0.68) | NR3C1PGRTNF | |
| SCHEMBL26158573 | 0.88 | NR3C1 (0.65) | NR3C1PGRTNF | |
| SCHEMBL3144658 | 0.87 | NR3C1 (0.74) | NR3C1PGRTNF | |
| SCHEMBL23622240 | 0.86 | NR3C1 (0.70) | NR3C1PGRTNF | |
| SCHEMBL23618939 | 0.86 | NR3C1 (0.61) | NR3C1PGRTNF | |
| SCHEMBL23622152 | 0.86 | NR3C1 (0.72) | NR3C1PGRTNF | |
| SCHEMBL23622241 | 0.85 | NR3C1 (0.71) | NR3C1PGRTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167068-A1 | BENZOPYRAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-20230167068-A1 | BENZOPYRAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-06-01 | — | — | US | disclosed |
| WO-2021136429-A1 | BENZOPYRAZOLE COMPOUND | 南京明德新药研发有限公司 | 2021-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167068-A1 | BENZOPYRAZOLE COMPOUND | ABCB1, CYP3A43, CYP3A5 | NR3C1 3472/4885PGR 1972/4885TNF 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.