SCHEMBL23622653

SCHEMBL23622653

c1ccc([Si](c2ccccc2)(c2ccc(-c3cc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)c3)cc2)c2ccc(-c3cc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)c3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 1/20 0.32
HDAC4 P56524 1/20 0.32
MKNK1 Q9BUB5 1/20 0.31
MKNK2 Q9HBH9 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30
TUBA3C P0DPH7 1/20 0.30
TUBA1B P68363 1/20 0.30
TUBA4A P68366 1/20 0.30
TUBB4B P68371 1/20 0.30
TUBB3 Q13509 1/20 0.30
TUBB2A Q13885 1/20 0.30
TUBB8 Q3ZCM7 1/20 0.30
TUBA3E Q6PEY2 1/20 0.30
TUBA1A Q71U36 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23622704 1.00 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1HDAC4
SCHEMBL23622725 0.94 L3MBTL1 (0.46) KDM4EATML3MBTL1ALDH1A1HDAC4
SCHEMBL23622651 0.93 HTT (0.38) KDM4EATML3MBTL1TSHRSMN1; SMN2
SCHEMBL23622423 0.91 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1
SCHEMBL23622750 0.91 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1
SCHEMBL23622424 0.91 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1
SCHEMBL25564938 0.91 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1MKNK1
SCHEMBL23622657 0.91 KDM4E (0.42) KDM4EATML3MBTL1ALDH1A1HDAC4
SCHEMBL23622148 0.91 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL23622189 0.88 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363254-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230363254-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-11716899-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-11716899-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-20210210700-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-07-08 US disclosed