Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710244 | 0.86 | MAPK1 (0.43) | MAPK1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30420441 | 0.86 | MAPK1 (0.43) | MAPK1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17008727 | 0.85 | MAPK1 (0.46) | MAPK1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30019960 | 0.85 | MAPK1 (0.46) | MAPK1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12066239 | 0.83 | MAPK1 (0.47) | MAPK1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7454206 | 0.81 | MAPK1 (0.46) | MAPK1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1105939 | 0.81 | ALDH1A1 (0.46) | MAPK1SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL30773331 | 0.81 | MAPK1 (0.42) | MAPK1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24369506 | 0.81 | MAPK1 (0.42) | MAPK1MRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23623115 | 0.79 | SMN1; SMN2 (0.38) | MAPK1NPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601158-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-15 | — | — | CN | disclosed |
| WO-2022076622-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |
| WO-2021138434-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-07-08 | — | — | WO | disclosed |