SCHEMBL23623472

SCHEMBL23623472

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccccc4)c4sc5c(-n6c7ccccc7c7c8oc9ccccc9c8ccc76)cccc5c34)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.33
ALDH1A1 P00352 4/20 0.33
LMNA P02545 4/20 0.33
KDM4E B2RXH2 3/20 0.33
TSHR P16473 3/20 0.33
HSD17B10 Q99714 2/20 0.33
POLB P06746 2/20 0.33
MAPK1 P28482 1/20 0.33
CYP17A1 P05093 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HPGD P15428 1/20 0.31
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
CDC14B O60729 1/20 0.30
CDC14A Q9UNH5 1/20 0.30
USP2 O75604 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25732604 0.92 TSHR (0.32) MAPTTSHR
SCHEMBL23623396 0.89 MAPT (0.33) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL22487670 0.88 TSHR (0.32) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL25732330 0.88 MAPT (0.32) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL24738432 0.87 ALOX5 (0.34) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL23156440 0.87 TSHR (0.34) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL21667031 0.87 TSHR (0.34) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL21925498 0.87 ALOX5 (0.35) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL16442565 0.87 TSHR (0.34) MAPTALDH1A1LMNAKDM4ETSHR
SCHEMBL16442498 0.87 ALOX5 (0.35) MAPTALDH1A1LMNAKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230147015-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2023-05-11 US disclosed
US-20230147015-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2023-05-11 US disclosed
WO-2021137565-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2021-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230147015-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER CYP1B1, NOTUM, CYP4F11 MAPT 1219/4885ALDH1A1 67/4885LMNA 2243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.