SCHEMBL23623723

SCHEMBL23623723

c1ccc(-c2ccc(-c3nc4ccccc4n3-c3ccccc3)c3c2oc2c(-c4ccc5oc6ccccc6c5c4)cccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.40
ESR1 P03372 3/20 0.38
ESR2 Q92731 3/20 0.38
RPS6KB1 P23443 3/20 0.38
PRKACA P17612 1/20 0.38
GSK3B P49841 1/20 0.38
ROCK1 Q13464 1/20 0.38
ALOX5 P09917 1/20 0.37
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
RAB9A P51151 1/20 0.36
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
PTGER4 P35408 1/20 0.34
GRIA1 P42261 1/20 0.33
CACNG8 Q8WXS5 1/20 0.33
CACNG2 Q9Y698 1/20 0.33
GGPS1 O95749 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25732233 0.89 RECQL (0.39) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL12349449 0.87 ALOX5 (0.46) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL23623552 0.87 ESR1 (0.44) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL21891306 0.87 RECQL (0.40) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL12349359 0.86 ALOX5 (0.45) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL12349416 0.85 ALOX5 (0.44) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL22177816 0.85 RECQL (0.39) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL23623580 0.85 RECQL (0.43) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL18314571 0.85 ALOX5 (0.42) RECQLESR1ESR2RPS6KB1PRKACA
SCHEMBL22177688 0.85 RECQL (0.42) RECQLESR1ESR2RPS6KB1PRKACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230147015-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2023-05-11 US disclosed
US-20230147015-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2023-05-11 US disclosed
WO-2021137565-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2021-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230147015-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER CYP1B1, NOTUM, CYP4F11 RECQL 2514/4885ESR1 418/4885ESR2 2040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.