Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362380 | 1.00 | GRIK1 (0.36) | GRIK1GRIK2FFAR3CA1CA2 | |
| SCHEMBL1486834 | 0.84 | FFAR3 (0.38) | GRIK1GRIK2FFAR3SOAT1 | |
| SCHEMBL800066 | 0.82 | — | — | |
| SCHEMBL164680 | 0.82 | — | — | |
| SCHEMBL28176230 | 0.82 | — | — | |
| SCHEMBL5792188 | 0.78 | ALDH1A1 (0.39) | GRIK1GRIK2FFAR3 | |
| SCHEMBL1614543 | 0.78 | ALDH1A1 (0.39) | GRIK1GRIK2FFAR3 | |
| SCHEMBL1614538 | 0.78 | ALDH1A1 (0.39) | GRIK1GRIK2FFAR3 | |
| SCHEMBL27862570 | 0.75 | SOAT1 (0.40) | CA1CA2SOAT1 | |
| SCHEMBL2351933 | 0.73 | GRIK1 (0.32) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358663-A1 | ENANTIOSELECTIVE SYNTHESIS OF -AMINO- , -UNSATURATED CARBOXYLIC ACID DERIVATIVES | Novartis AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010055162-A1 | ENANTIOSELECTIVE SYNTHESIS OF γ-AMINO-α,β-UNSATURATED CARBOXYLIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2010-05-20 | — | — | WO | disclosed |