Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 5/20 | 0.54 |
| ▸ | FNTA | P49354 | 8/20 | 0.40 |
| ▸ | FNTB | P49356 | 8/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278342 | 0.96 | CXCR3 (0.58) | CXCR3FNTAFNTBWDR5F10 | |
| SCHEMBL2271426 | 0.92 | CXCR3 (0.62) | CXCR3RORCF10 | |
| SCHEMBL12515554 | 0.89 | CXCR3 (0.50) | CXCR3FNTAFNTBWDR5 | |
| SCHEMBL2275602 | 0.89 | CXCR3 (0.50) | CXCR3FNTAFNTBWDR5 | |
| SCHEMBL2361498 | 0.89 | CXCR3 (0.44) | CXCR3FNTAFNTBWDR5RORC | |
| SCHEMBL2268986 | 0.88 | CXCR3 (0.62) | CXCR3 | |
| SCHEMBL2222624 | 0.88 | CXCR3 (0.49) | CXCR3FNTAFNTBWDR5F10 | |
| SCHEMBL2269437 | 0.87 | CXCR3 (0.48) | CXCR3RORC | |
| SCHEMBL2269078 | 0.87 | CXCR3 (0.48) | CXCR3FNTAFNTBWDR5RORC | |
| SCHEMBL2267627 | 0.87 | CXCR3 (0.50) | CXCR3FNTAFNTBWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084985-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-14 | — | — | WO | disclosed |