Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184665 | 0.85 | SMN1; SMN2 (0.59) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL358860 | 0.85 | SMN1; SMN2 (0.59) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL3259829 | 0.83 | TSHR (0.68) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL30291384 | 0.81 | MAPT (0.55) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8777970 | 0.81 | MAPT (0.55) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL23624991 | 0.81 | POLB (0.47) | MAPTALDH1A1POLBCA1CA2 | |
| SCHEMBL23625105 | 0.81 | ALDH1A1 (0.54) | MAPTALDH1A1TSHRHSD17B10HTT | |
| SCHEMBL23624955 | 0.81 | MAPT (0.49) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL14988893 | 0.80 | MAPT (0.54) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL155420 | 0.80 | MAPT (0.54) | MAPTALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021138392-A1 | AMINOPYRIMIDINE COMPOUNDS | TYRA BIOSCIENCES, INC. (US) | 2021-07-08 | — | — | WO | disclosed |