SCHEMBL23625630

SCHEMBL23625630

N#Cc1c2ccccc2c(I)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 3/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
CACNA1B Q00975 1/20 0.50
APBA1 Q02410 1/20 0.50
DYRK1A Q13627 4/20 0.42
EGFR P00533 1/20 0.37
SRC P12931 1/20 0.37
TSHR P16473 1/20 0.36
IMPDH2 P12268 3/20 0.34
IMPDH1 P20839 2/20 0.34
PDE9A O76083 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
APAF1 O14727 1/20 0.33
MAPK1 P28482 1/20 0.33
STAT3 P40763 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429129 0.87 ALDH1A1 (0.64) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL150623 0.87 ALDH1A1 (0.64) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL148856 0.78 ALDH1A1 (0.59) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL2546104 0.78 ALDH1A1 (0.59) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL1133452 0.78 ALDH1A1 (0.41) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL29549717 0.78 ALDH1A1 (0.41) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL16213053 0.77 TSHR (0.57) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL20549063 0.75 KDM4E (0.52) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL5751189 0.75 ALDH1A1 (0.52) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL24617849 0.75 ALDH1A1 (0.52) ALDH1A1KDM4EMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135516-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed