SCHEMBL23625938

SCHEMBL23625938

CC1(C)OB(c2ccc3c(c2)C2(c4ccccc4-3)C3CC4CC5CC2C53C4)OC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPL P06858 5/20 0.34
LIPG Q9Y5X9 5/20 0.34
ROCK1 Q13464 1/20 0.31
HIF1A Q16665 1/20 0.31
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23625944 0.94 LPL (0.34) LPLLIPGROCK1HIF1APRMT5
SCHEMBL24626838 0.86 LPL (0.36) LPLLIPGROCK1HIF1APRMT5
SCHEMBL24272493 0.84 LPL (0.33) LPLLIPGHIF1A
SCHEMBL22797496 0.83 LPL (0.39) LPLLIPGROCK1HIF1APRMT5
SCHEMBL25896413 0.83 LPL (0.39) LPLLIPGROCK1HIF1APRMT5
SCHEMBL23625943 0.79 LPL (0.36) LPLLIPGROCK1HIF1APRMT5
SCHEMBL23626268 0.78 LPL (0.35) LPLLIPGROCK1PRMT5WDR77
SCHEMBL25818739 0.77 LPL (0.35) LPLLIPGROCK1HIF1APRMT5
SCHEMBL25491171 0.77 PDK2 (0.42)
SCHEMBL24622897 0.77 LPL (0.34) LPLLIPGPRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135181-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed