SCHEMBL23625958

SCHEMBL23625958

N#Cc1ccc(-c2nc(N)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 9/20 0.62
ADORA2A P29274 8/20 0.62
ADORA3 P0DMS8 2/20 0.62
ADORA2B P29275 2/20 0.62
POLB P06746 1/20 0.62
HRH4 Q9H3N8 1/20 0.57
ABCG2 Q9UNQ0 7/20 0.54
ABCB1 P08183 4/20 0.54
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.50
HSP90AA1 P07900 1/20 0.49
HSP90AB1 P08238 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
KMT2A Q03164 1/20 0.49
ABCC1 P33527 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663591 0.91 ABCG2 (0.62) ADORA1ADORA2AABCG2ABCB1TSHR
SCHEMBL31042623 0.89 HRH4 (0.59) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL22106575 0.89 ABCG2 (0.60) ABCG2ABCB1TSHRABCC1
SCHEMBL22360641 0.89 ABCG2 (0.60) ABCG2ABCB1TSHRABCC1
SCHEMBL20396079 0.89 ABCG2 (0.60) ABCG2ABCB1TSHRABCC1
SCHEMBL23383850 0.89 ABCG2 (0.60) ABCG2ABCB1TSHRABCC1
SCHEMBL23384091 0.89 ABCG2 (0.60) ABCG2ABCB1TSHRABCC1
SCHEMBL23383904 0.89 ABCG2 (0.60) ABCG2ABCB1TSHRABCC1
SCHEMBL22883053 0.89 ABCG2 (0.60) ABCG2ABCB1TSHRABCC1
SCHEMBL19939303 0.89 ABCG2 (0.60) ABCG2ABCB1TSHRABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135181-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed