SCHEMBL23625985

SCHEMBL23625985

c1ccc(-c2ccc(-n3c4ccccc4c4c(-c5cccc6c5-c5ccccc5C65C6CC7CC8CC5C786)cccc43)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23625995 0.88
SCHEMBL25054849 0.87 HDAC4 (0.33) HDAC4KDM4EATML3MBTL1
SCHEMBL23626000 0.84 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL25054638 0.81 DHODH (0.33)
SCHEMBL25054809 0.81 HTT (0.30)
SCHEMBL23626018 0.81 DHODH (0.30)
SCHEMBL25054850 0.80 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL23605954 0.79
SCHEMBL25054793 0.79 WNK1 (0.31) KDM4EATML3MBTL1
SCHEMBL24626611 0.78 KDM4E (0.32) HDAC4KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135181-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed