Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23626398 | 1.00 | MEN1 (0.42) | MEN1GAAKMT2ATDP1SYK | |
| SCHEMBL570033 | 0.85 | MEN1 (0.50) | MEN1GAAKMT2ATDP1SYK | |
| SCHEMBL25867028 | 0.84 | MEN1 (0.39) | MEN1GAAKMT2ATDP1SYK | |
| SCHEMBL17144776 | 0.83 | MEN1 (0.51) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL19849083 | 0.82 | MEN1 (0.38) | MEN1GAAKMT2ATDP1SYK | |
| SCHEMBL29678502 | 0.82 | MEN1 (0.38) | MEN1GAAKMT2ATDP1SYK | |
| SCHEMBL2749935 | 0.82 | MEN1 (0.45) | MEN1GAAKMT2ATDP1SYK | |
| SCHEMBL1224366 | 0.82 | MEN1 (0.45) | MEN1GAAKMT2ATDP1SYK | |
| SCHEMBL1224364 | 0.82 | MEN1 (0.45) | MEN1GAAKMT2ATDP1SYK | |
| SCHEMBL28908649 | 0.81 | MEN1 (0.42) | MEN1GAAKMT2ATDP1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222646-A | KRAS G12C inhibitors and uses thereof | 苏州赞荣医药科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| WO-2021136808-A1 | CONJUGATES UNDERGOING INTRAMOLECULAR REARRANGEMENTS | ASCENDIS PHARMA A/S (DK) | 2021-07-08 | — | — | WO | disclosed |