SCHEMBL570033

SCHEMBL570033

CC(C)(C)OC(=O)NCC(O)CNC(=O)OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA7 P43166 1/20 0.43
SYK P43405 1/20 0.42
SERPINE1 P05121 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
CYP2D6 P10635 1/20 0.42
CTSS P25774 3/20 0.41
CTSK P43235 3/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
APLNR P35414 1/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CA12 O43570 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16379307 0.94 MEN1 (0.46) MEN1GAAKMT2ATDP1CA1
SCHEMBL13960156 0.94 MEN1 (0.46) MEN1GAAKMT2ATDP1CA1
SCHEMBL12475162 0.92 MEN1 (0.49) MEN1GAAKMT2ATDP1CA1
SCHEMBL2284087 0.92 MEN1 (0.45) MEN1GAAKMT2ATDP1CA1
SCHEMBL15571118 0.91 MEN1 (0.44) MEN1GAAKMT2ATDP1CA1
SCHEMBL15571119 0.91 MEN1 (0.44) MEN1GAAKMT2ATDP1CA1
SCHEMBL1222350 0.90 TDP1 (0.49) MEN1GAAKMT2ATDP1CA1
SCHEMBL1222348 0.90 TDP1 (0.49) MEN1GAAKMT2ATDP1CA1
SCHEMBL5352030 0.90 MEN1 (0.46) MEN1GAAKMT2ATDP1CA1
SCHEMBL3166361 0.90 TDP1 (0.49) MEN1GAAKMT2ATDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529639-A Anticorrosive phenolic epoxy resin coating for oil pipe and preparation method thereof 上海泰梧科技有限公司 2025-02-28 CN claimed
CN-117209887-B High-toughness durable polypropylene material and preparation process thereof 珠海市金塑塑料有限公司 2024-04-16 CN claimed
CN-117209887-A High-toughness durable polypropylene material and preparation process thereof 广东科净塑料制品有限公司 2023-12-12 CN claimed
US-20260008777-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-08 US disclosed
US-12358951-B2 Cyclic peptide antibiotics GENENTECH, INC. (US) 2025-07-15 US disclosed
EP-3592761-B1 NEW ANTIBACTERIAL PRODUCTS UNIV LIVERPOOL (GB) 2025-05-14 EP disclosed
CN-119529639-A Anticorrosive phenolic epoxy resin coating for oil pipe and preparation method thereof 上海泰梧科技有限公司 2025-02-28 CN disclosed
US-20240374595-A1 SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2024-11-14 US disclosed
US-20240327463-A1 ANTIBACTERIAL PRODUCTS THE UNIVERSITY OF LIVERPOOL (GB) 2024-10-03 US disclosed
US-12083118-B2 Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same ARBUTUS BIOPHARMA CORPORATION (CA) 2024-09-10 US disclosed
EP-3868409-B1 THIOPHENOL-MALEIMIDE AND BROM-MALEIMIDE DERIVATIVES AS LINKER FOR ANTIBODY-DRUG CONJUGATES (ADC) FOR TREATING TUMORS REMEGEN CO LTD (CN) 2024-07-17 EP disclosed
US-5808091-A DIAGNOSTIC IMAGING AGENT BRACCO INTERNATIONAL B.V. 1998-09-15 US disclosed
US-5712417-A Inhibitors of retroviral proteases ABBOTT LABORATORIES (US) 1998-01-27 US disclosed
US-5688487-A Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety BRACCO INTERNATIONAL B.V. (NL) 1997-11-18 US disclosed
EP-0544412-B1 Rhenium and technetium complexes containing a hypoxia-localizing moiety BRACCO INT BV (NL) 1997-07-23 EP disclosed
EP-0544412-A2 Rhenium and technetium complexes containing a hypoxia-localizing moiety BRACCO INTERNATIONAL B.V. (NL) 1993-06-02 EP disclosed
EP-0428849-A2 Retroviral protease inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-29 EP disclosed
US-4933470-A Method of synthesis of vicinal diamines NEORX CORPORATION (US) 1990-06-12 US disclosed
EP-0144825-B1 CYCLIC GUANIDINYL THIO CARBAPENEMS MERCK & CO. INC. (US) 1989-07-05 EP disclosed
US-4717728-A ANTIBIOTICS MERCK & CO., INC. (US) 1988-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12083118-B2 Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same HAVCR2, HMBS, BCL3 MEN1 1368/4885GAA 2530/4885KMT2A 383/4885
US-12358951-B2 Cyclic peptide antibiotics NPPA, LNPEP, CLPP MEN1 4359/4885GAA 844/4885KMT2A 1737/4885
US-20260008777-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE PTPRO, PTPRC, PTPRR MEN1 4235/4885GAA 3227/4885KMT2A 1717/4885
US-20240374595-A1 SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME HAVCR2, HMBS, CDV3 MEN1 1507/4885GAA 2288/4885KMT2A 400/4885
US-20240327463-A1 ANTIBACTERIAL PRODUCTS DBI, PDIA5, ABCB11 MEN1 2942/4885GAA 504/4885KMT2A 4485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.