Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698958 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL14709158 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL28489991 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL12280418 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL15859653 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL1834044 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL14709006 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL1509195 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL1255498 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI | |
| SCHEMBL12910763 | 1.00 | MGAM (0.33) | MGAMCA1CA2GAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160320-B | Preparation method of chiral pyrimido triazole ticagrelor | 南通常佑药业科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-115160320-A | Preparation method of chiral pyrimidotriazole ticagrelor | 南通常佑药业科技有限公司 | 2022-10-11 | — | — | CN | disclosed |
| EP-2536695-A1 | IMPROVED PROCESSES FOR PREPARING TICAGRELOR INTERMEDIATE, 4,6-DICHLORO-5-NITRO-2-(PROPYLTHIO)PYRIMIDINE | Actavis Group Ptc Ehf (IS) | 2012-12-26 | — | — | EP | disclosed |
| WO-2012063126-A2 | IMPROVED PROCESSES FOR PREPARING PURE (3AR,4S,6R,6AS)-6-AMINO-2,2-DIMETHYLTETRAHDRO-3AH-CYCLOPENTA[D] [1,3]-DIOXOL-4-OL AND ITS KEY STARTING MATERIAL | ACTAVIS GROUP PTC EHF (IS) | 2012-05-18 | — | — | WO | disclosed |
| WO-2011101740-A1 | IMPROVED PROCESSES FOR PREPARING TICAGRELOR INTERMEDIATE, 4,6-DICHLORO-5-NITRO-2-(PROPYLTHIO)PYRIMIDINE | ACTAVIS GROUP PTC EHF (IS) | 2011-08-25 | — | — | WO | disclosed |
| EP-1299390-A1 | NOVEL TRIAZOLO PYRIMIDINE COMPOUNDS | AstraZeneca AB (SE) | 2003-04-09 | — | — | EP | disclosed |
| WO-2001092263-A1 | NOVEL TRIAZOLO PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2001-12-06 | — | — | WO | disclosed |