SCHEMBL23627242

SCHEMBL23627242

C=CCCS(=O)(CCC)=NC

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12555388 0.82 CA1 (0.35)
SCHEMBL24773885 0.71
SCHEMBL7820391 0.67
SCHEMBL11911269 0.65 TSHR (0.37) TSHRALDH1A1
Dimethyl Sulfone SCHEMBL3793667 0.64 TSHR (0.71) TSHRALDH1A1
SCHEMBL6601699 0.64
SCHEMBL11328103 0.64 TSHR (0.50) TSHRALDH1A1
SCHEMBL4442903 0.63 CA2 (0.40) TSHRALDH1A1
Sulfuric Acid SCHEMBL3096243 0.62 TSHR (0.67) TSHRALDH1A1
SCHEMBL9720004 0.62 TSHR (0.67) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021138391-A1 INDAZOLE COMPOUNDS TYRA BIOSCIENCES, INC. (US) 2021-07-08 WO disclosed