Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928722 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10MAPK1TDP1 | |
| SCHEMBL11489974 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10MAPK1MEN1 | |
| SCHEMBL8393450 | 0.88 | HSD17B10 (0.44) | ALDH1A1TSHRHSD17B10TDP1USP2 | |
| SCHEMBL11439282 | 0.84 | HSD17B10 (0.46) | ALDH1A1TSHRHSD17B10MAPK1TDP1 | |
| SCHEMBL1450274 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10TDP1THRB | |
| SCHEMBL5980539 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10MAPK1TDP1 | |
| SCHEMBL9488328 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10MAPK1TDP1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL1076753 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL8537650 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10MAPK1TDP1 | |
| SCHEMBL28092556 | 0.83 | TSHR (0.45) | ALDH1A1TSHRHSD17B10MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130118238-A1 | TEST SOLVENT FOR EVALUATING THE COMPATIBILITY OF BIOLOGICALLY ACTIVE SUBSTANCES AND GRAFT COPOLYMERS | ABBOTT GMBH & CO. KG (DE) | 2013-05-16 | — | — | US | claimed |
| EP-2536393-A2 | TEST SOLVENT FOR EVALUATING THE COMPATIBILITY OF BIOLOGICALLY ACTIVE SUBSTANCES AND GRAFT COPOLYMERS | Abbott GmbH & Co. KG (DE) | 2012-12-26 | — | — | EP | claimed |
| WO-2011101352-A2 | TEST SOLVENT FOR EVALUATING THE COMPATIBILITY OF BIOLOGICALLY ACTIVE SUBSTANCES AND GRAFT COPOLYMERS | ABBOTT GMBH & CO. KG (DE) | 2011-08-25 | — | — | WO | claimed |
| US-4204972-A | Hydraulic fluids comprising nitrogen-containing boric acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-27 | — | — | US | disclosed |