Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18668465 | 0.98 | L3MBTL1 (0.40) | L3MBTL1MEN1KMT2ACETPKDM4E | |
| SCHEMBL25219070 | 0.88 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2ACETPKDM4E | |
| SCHEMBL23628469 | 0.86 | KDM4E (0.46) | L3MBTL1CETPKDM4EALDH1A1HPGD | |
| SCHEMBL3710643 | 0.82 | MAPKAPK2 (0.45) | KMT2ALMNA | |
| SCHEMBL23628496 | 0.78 | L3MBTL1 (0.43) | L3MBTL1MEN1KMT2ACETPKDM4E | |
| SCHEMBL23628464 | 0.78 | KDM4E (0.40) | L3MBTL1MEN1KMT2ACETPKDM4E | |
| SCHEMBL23628473 | 0.74 | CETP (0.47) | L3MBTL1CETPKDM4EALDH1A1HPGD | |
| SCHEMBL29572276 | 0.72 | KDM4E (0.49) | L3MBTL1MEN1KMT2ACETPKDM4E | |
| SCHEMBL18668416 | 0.72 | KDM4E (0.49) | L3MBTL1MEN1KMT2ACETPKDM4E | |
| SCHEMBL23628475 | 0.72 | KMT2A (0.41) | L3MBTL1MEN1KMT2ACETPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353178-B1 | BICYCLIC COMPOUNDS AS DUAL ATX/CA INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-07-14 | — | — | EP | disclosed |