Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23575565 | 0.91 | CSF1R (0.51) | CSF1RPDE4BGAAMEN1KMT2A | |
| SCHEMBL23575759 | 0.91 | CSF1R (0.47) | CSF1RPDE4BGAAMEN1KMT2A | |
| SCHEMBL23575470 | 0.88 | CSF1R (0.51) | CSF1RPDE4BGAAMEN1KMT2A | |
| SCHEMBL23575367 | 0.82 | CSF1R (0.53) | CSF1RPDE4BMAPTLMNANPSR1 | |
| SCHEMBL23575445 | 0.78 | PDE4B (0.46) | CSF1RPDE4B | |
| SCHEMBL23575650 | 0.77 | CSF1R (0.57) | CSF1RPDE4BMTOR | |
| SCHEMBL23629075 | 0.77 | CSF1R (0.56) | CSF1RPDE4B | |
| SCHEMBL23575654 | 0.76 | CSF1R (0.59) | CSF1RPDE4BMTOR | |
| SCHEMBL23629074 | 0.74 | CSF1R (0.62) | CSF1RSLC2A1 | |
| SCHEMBL23200447 | 0.73 | MEN1 (0.48) | GAAMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846800-A1 | COMPOUNDS FOR THE DEGRADATION OF BRD9 OR MTH1 | C4 Therapeutics, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |