Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23575743 | 0.88 | CSF1R (0.62) | CSF1RLRRK2CYP3A4CYP2C9 | |
| SCHEMBL23575564 | 0.87 | CSF1R (0.54) | CSF1RSLC2A1LRRK2CYP3A4CYP2C9 | |
| SCHEMBL23575654 | 0.80 | CSF1R (0.59) | CSF1R | |
| SCHEMBL23575650 | 0.80 | CSF1R (0.57) | CSF1R | |
| SCHEMBL23575367 | 0.78 | CSF1R (0.53) | CSF1R | |
| SCHEMBL23575446 | 0.77 | CSF1R (0.74) | CSF1RLRRK2CYP3A4CYP2C9 | |
| SCHEMBL31673833 | 0.77 | CSF1R (0.83) | CSF1RLRRK2 | |
| SCHEMBL23575565 | 0.76 | CSF1R (0.51) | CSF1RSLC2A1 | |
| SCHEMBL4761193 | 0.76 | CSF1R (0.72) | CSF1RLRRK2CYP3A4CYP2C9 | |
| SCHEMBL30864154 | 0.76 | CSF1R (0.72) | CSF1RLRRK2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846800-A1 | COMPOUNDS FOR THE DEGRADATION OF BRD9 OR MTH1 | C4 Therapeutics, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |