Piperidine

Piperidine

SCHEMBL28823404

C1CCNCC1.c1ccc(C(NC(c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 2/20 0.41
CYP2D6 P10635 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
HRH1 P35367 1/20 0.40
SCN1A P35498 1/20 0.40
KMT2A Q03164 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
ALDH1A1 P00352 2/20 0.38
KIF11 P52732 1/20 0.35
CYP2B6 P20813 1/20 0.34
SIGMAR1 Q99720 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL28823413 0.98 KCNN4 (0.43) KCNN4CYP2D6MEN1LMNAHRH1
SCHEMBL2363005 0.79 KCNN4 (0.60) KCNN4ALDH1A1KIF11CYP1A2MAPK1
Ammonia Solution, Strong SCHEMBL28866362 0.77 KCNN4 (0.57) KCNN4ALDH1A1KIF11CYP1A2MAPK1
Hydrogen Sulfide SCHEMBL28100574 0.77 KCNN4 (0.57) KCNN4ALDH1A1KIF11CYP1A2MAPK1
Chlorotriphenylmethane SCHEMBL28247644 0.75 TSHR (0.41) CYP2D6MEN1LMNAHRH1SCN1A
Ammonia Solution, Strong SCHEMBL28252125 0.74 KCNN4 (0.55) KCNN4ALDH1A1KIF11CYP1A2MAPK1
Methylamine SCHEMBL28272974 0.72 KCNN4 (0.59) KCNN4KMT2AALDH1A1KIF11MAPK1
Biphenyl SCHEMBL10773004 0.72 ALDH1A1 (0.50) CYP2D6MEN1KMT2AALDH1A1SIGMAR1
N-Methylpiperidine SCHEMBL28869132 0.72 CYP2B6 (0.48) KCNN4CYP2D6MEN1LMNASCN1A
Diphenylamine SCHEMBL1933551 0.71 HSD17B10 (0.57) MEN1LMNAKMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105576325-A BIPHASE ELECTROLYTE FOR A METAL-AIR BATTERY TOYOTA MOTOR ENG AND MFG NORTH AMERICA INC 2016-05-11 CN claimed
CN-105576325-A BIPHASE ELECTROLYTE FOR A METAL-AIR BATTERY TOYOTA MOTOR ENG AND MFG NORTH AMERICA INC 2016-05-11 CN disclosed
CN-105514528-A Electrode catalyst TOYOTA MOTOR CO LTD 2016-04-20 CN disclosed
CN-104969386-A COMPOSITE ACTIVE MATERIAL, MANUFACTURING METHOD FOR COMPOSITE ACTIVE MATERIAL, AND LITHIUM SECONDARY BATTERY INCLUDING COMPOSITE ACTIVE MATERIAL TOYOTA MOTOR CORP 2015-10-07 CN disclosed