Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL23630136

CC(C)[C@H](NC(=O)CNC(=O)CN)C(=O)N[C@@H](CCCNC(N)=O)C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ QRFPR Q96P65 3/20 0.39
▸ C3AR1 Q16581 1/20 0.38
▸ FURIN P09958 8/20 0.38
▸ NPY1R P25929 4/20 0.37
▸ NPY4R P50391 1/20 0.35
▸ PRSS1 P07477 1/20 0.35
▸ SHMT1 P34896 1/20 0.35
▸ CTDSP1 Q9GZU7 1/20 0.34
▸ CTSB P07858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24191073 0.94 C3AR1 (0.42) QRFPRC3AR1FURINPRSS1SHMT1
SCHEMBL31319761 0.93 C3AR1 (0.41) QRFPRC3AR1FURINPRSS1SHMT1
Trifluoroacetic Acid SCHEMBL31075769 0.91 QRFPR (0.37) QRFPRC3AR1NPY1R
Trifluoroacetic Acid SCHEMBL23630041 0.91 QRFPR (0.37) QRFPRC3AR1NPY1R
SCHEMBL29385639 0.87 C3AR1 (0.45) C3AR1FURINSHMT1CTDSP1
SCHEMBL6850333 0.85 FURIN (0.40) QRFPRFURINNPY1RNPY4RPRSS1
SCHEMBL6850341 0.85 FURIN (0.40) QRFPRFURINNPY1RNPY4RPRSS1
SCHEMBL30317564 0.85 C3AR1 (0.42) QRFPRC3AR1FURINPRSS1SHMT1
SCHEMBL24191266 0.84 C3AR1 (0.40) QRFPRC3AR1
SCHEMBL29620243 0.84 C3AR1 (0.42) C3AR1FURINPRSS1SHMT1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-29 — — US disclosed
EP-4524154-A2 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES Daiichi Sankyo Company, Limited (JP) 2025-03-19 — — EP disclosed
EP-3848054-B1 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2025-01-29 — — EP disclosed
US-20240293567-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-09-05 — — US disclosed
US-20220008549-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2022-01-13 — — US disclosed
EP-3848054-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF Daiichi Sankyo Company, Limited (JP) 2021-07-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates STING1, CGAS, CDA QRFPR 984/4885C3AR1 201/4885FURIN 2148/4885
US-20220008549-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF STING1, CGAS, TLR9 QRFPR 900/4885C3AR1 143/4885FURIN 1843/4885
US-20240293567-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF STING1, CGAS, TLR9 QRFPR 900/4885C3AR1 143/4885FURIN 1843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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