Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 8/20 | 0.40 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 7/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | TFPI | P10646 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850333 | 1.00 | FURIN (0.40) | FURINQRFPRNPY4RNPY1RNPY5R | |
| SCHEMBL29485118 | 0.93 | FURIN (0.40) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30087255 | 0.92 | FURIN (0.43) | FURINQRFPRNPY4RNPY1RNPY5R | |
| SCHEMBL24191073 | 0.91 | C3AR1 (0.42) | FURINQRFPRNOD1PRSS1 | |
| SCHEMBL31319761 | 0.90 | C3AR1 (0.41) | FURINQRFPRNOD1PRSS1 | |
| SCHEMBL30976568 | 0.89 | FURIN (0.48) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29355811 | 0.89 | NPY4R (0.41) | QRFPRNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30087281 | 0.88 | NOD1 (0.44) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30881182 | 0.88 | TFPI (0.46) | FURINQRFPRNPY4RNPY1RNPY5R | |
| SCHEMBL3961412 | 0.87 | QRFPR (0.46) | QRFPRNPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |
| WO-2001079195-A9 | PYRIDINE AND PYRAZINE DERIVATIVES AS THROMBIN INHIBITORS | CORVAS INT INC (US) | 2003-10-23 | — | — | WO | disclosed |
| US-6541467-B1 | And at P1 have a six-membered heterocyclic ring having two ring nitrogen ring atoms and the remainder of the ring atoms carbon atoms. | CORVAS INTERNATIONAL, INC. | 2003-04-01 | — | — | US | disclosed |
| US-6506754-B1 | Compounds as anticoagulants | CORVAS INTERNATIONAL, INC. | 2003-01-14 | — | — | US | disclosed |
| US-6506761-B1 | Compound of the invention are active as inhibitors of Thrombin and are useful in treating disease states in mammals which are characterized by abnormal thrombosis and have the following structure: | CORVAS INTERNATIONAL, INC. | 2003-01-14 | — | — | US | disclosed |
| US-6506760-B1 | Compounds of the invention are active as inhibitors of Thrombin and are useful in treating disease states in mammals which are characterized by abnormal thrombosis and have the following structure: | CORVAS INTERNATIONAL, INC. | 2003-01-14 | — | — | US | disclosed |
| US-6342504-B1 | PEPTIDES AS ANTITHROMBINS AND ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2002-01-29 | — | — | US | disclosed |
| WO-2001079195-A2 | PYRIDINE AND PYRAZINE DERIVATIVES AS THROMBIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
| WO-2001079193-A2 | SUBSTITUTED HYDRAZINYL HETEROAROMATIC INHIBITORS OF THROMBIN | CORVAS INTERNATIONAL, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
| WO-2001079262-A1 | PYRAZINONE AND PYRIDINONE DERIVATIVES AS THROMBIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
| WO-1995035313-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES CONTAINING AN ARGININE MIMIC AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995035312-A1 | ARGININE MIMIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995035311-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-28 | — | — | WO | disclosed |
| EP-0684830-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1995028420-A1 | METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-10-26 | — | — | WO | disclosed |
| EP-0627929-A4 | INHIBITORS OF THROMBOSIS. | CORVAS INT INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0627929-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-12-14 | — | — | EP | disclosed |
| WO-1994021673-A1 | ALPHA-KETOAMIDE DERIVATIVES AS INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-09-29 | — | — | WO | disclosed |
| WO-1994017817-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-08-18 | — | — | WO | disclosed |
| WO-1993015756-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1993-08-19 | — | — | WO | disclosed |