SCHEMBL23630237

SCHEMBL23630237

CC=CC(=O)SCc1ccc(CSC(=O)C=CC)cc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.40
IDO1 P14902 13/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP3A4 P08684 2/20 0.34
LMNA P02545 1/20 0.34
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23630236 0.74 NOS1 (0.43) NOS1IDO1THRATHRBTDP1
SCHEMBL16116290 0.73 IDO1 (0.48) NOS1IDO1TDP1L3MBTL1NOS3
SCHEMBL23630231 0.72 APP (0.34)
SCHEMBL20169330 0.71 NOS1 (0.41) NOS1IDO1TDP1CYP3A4NOS3
SCHEMBL10823737 0.70
SCHEMBL23630235 0.69 APP (0.33)
SCHEMBL2718707 0.67 CYP2C19 (0.39) THRB
SCHEMBL2718709 0.67 CYP2C19 (0.39) THRB
SCHEMBL3077760 0.66 NPC1 (0.51) NOS1IDO1THRBTDP1L3MBTL1
SCHEMBL3077763 0.66 NPC1 (0.51) NOS1IDO1THRBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4065341-B1 INKJET METHOD FOR PRODUCING A SPECTACLE LENS ZEISS CARL VISION INT GMBH (DE) 2023-11-29 EP disclosed
US-11794428-B2 Inkjet method for producing a spectacle lens CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2023-10-24 US disclosed
EP-3848179-A1 INKJET METHOD FOR PRODUCING A SPECTACLE LENS Carl Zeiss Vision International GmbH (DE) 2021-07-14 EP disclosed