Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | IGF1R | P08069 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30202205 | 1.00 | TSHR (0.67) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL133054 | 0.80 | TSHR (1.00) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL6750152 | 0.80 | TSHR (1.00) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL29364667 | 0.80 | TSHR (1.00) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL1903290 | 0.80 | TSHR (1.00) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL8166670 | 0.80 | TSHR (1.00) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL13280 | 0.80 | TSHR (1.00) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL7154524 | 0.79 | TSHR (0.89) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL8881784 | 0.78 | TSHR (0.96) | TSHRIGF1RKMT2AMAPTKDM4E | |
| Dyrene SCHEMBL827164 | 0.78 | TSHR (0.96) | TSHRIGF1RKMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230101743-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2023-03-30 | — | — | US | claimed |
| WO-2021141984-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-07-15 | — | — | WO | claimed |
| US-20230101743-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2023-03-30 | — | — | US | disclosed |
| WO-2021141984-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-07-15 | — | — | WO | disclosed |
| WO-2021141984-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230101743-A1 | SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF | PCSK9, SLC10A1, CYP3A5 | TSHR 976/4885IGF1R 3314/4885KMT2A 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.