Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635317 | 0.92 | GRM2 (0.43) | GRM2AOC3KDM4EALDH1A1GAA | |
| SCHEMBL23630491 | 0.86 | NPC1 (0.38) | AOC3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL23630397 | 0.85 | AOC3 (0.38) | GRM2AOC3KDM4EALDH1A1GAA | |
| SCHEMBL23630493 | 0.81 | EPHX2 (0.39) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL23635295 | 0.80 | SMN1; SMN2 (0.39) | GRM2ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL23630586 | 0.80 | TIPARP (0.36) | AOC3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL23630458 | 0.78 | MAPT (0.41) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL23635303 | 0.78 | GRM2 (0.39) | GRM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL23635302 | 0.77 | LCAT (0.38) | GRM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL23635380 | 0.76 | GRM2 (0.44) | GRM2AOC3KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |