Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635382 | 0.86 | GRM2 (0.38) | GRM2SLC9A1KDM4EL3MBTL1MAPT | |
| SCHEMBL23635318 | 0.86 | RET (0.37) | SLC9A1KDM4EL3MBTL1MAPTHPGD | |
| SCHEMBL23635317 | 0.85 | GRM2 (0.43) | GRM2KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL23635381 | 0.83 | SLC9A1 (0.38) | GRM2SLC9A1KDM4EL3MBTL1MAPT | |
| SCHEMBL20565565 | 0.82 | GRM2 (0.45) | GRM2KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL23630347 | 0.80 | RXFP1 (0.38) | KDM4EL3MBTL1MAPTHPGDNPSR1 | |
| SCHEMBL23630438 | 0.79 | KDM4E (0.37) | KDM4EL3MBTL1MAPTHPGDNPSR1 | |
| SCHEMBL23635343 | 0.79 | KDM4E (0.34) | KDM4EL3MBTL1MAPTHPGDNPSR1 | |
| SCHEMBL23630439 | 0.76 | GRM2 (0.38) | GRM2KDM4EL3MBTL1MAPTHPGD | |
| SCHEMBL23635332 | 0.72 | L3MBTL1 (0.35) | KDM4EL3MBTL1MAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |