Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630688 | 1.00 | SERPINE1 (0.38) | SERPINE1POLBPOLA1ANTXR2NSD2 | |
| SCHEMBL21584398 | 0.92 | CNR1 (0.39) | SERPINE1NSD2CNR1TSHRHSD17B10 | |
| SCHEMBL24621905 | 0.90 | HIF1A (0.35) | SERPINE1CNR1SIRT2SIRT1SLC7A5 | |
| SCHEMBL26710713 | 0.88 | CNR1 (0.32) | CNR1 | |
| SCHEMBL23630689 | 0.88 | POLB (0.47) | SERPINE1POLBPOLA1ANTXR2NSD2 | |
| SCHEMBL23957510 | 0.88 | POLB (0.47) | SERPINE1POLBPOLA1ANTXR2NSD2 | |
| SCHEMBL23630719 | 0.88 | POLB (0.47) | SERPINE1POLBPOLA1ANTXR2NSD2 | |
| SCHEMBL30307918 | 0.88 | CNR1 (0.39) | CNR1SMN1; SMN2TSHRSIRT2SIRT1 | |
| SCHEMBL28551345 | 0.88 | CNR1 (0.39) | CNR1SMN1; SMN2TSHRSIRT2SIRT1 | |
| SCHEMBL23630726 | 0.87 | NSD2 (0.43) | SERPINE1POLBPOLA1ANTXR2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12521410-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2026-01-13 | — | — | US | disclosed |
| CN-112566894-B | Potent inhibitors of D-amino acid oxidase (DAAO) and uses thereof | 心悦生医股份有限公司 | 2025-01-17 | — | — | CN | disclosed |
| US-20240180945-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2024-06-06 | — | — | US | disclosed |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| CN-115836062-A | Compound and medical application thereof | 心悦生医股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4139275-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Syneurx International (Taiwan) Corp. (TW) | 2023-03-01 | — | — | EP | disclosed |
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2022-07-14 | — | — | US | disclosed |
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2022-07-14 | — | — | US | disclosed |
| WO-2021213500-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-10-28 | — | — | WO | disclosed |
| US-20210214385-A1 | INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2021-07-15 | — | — | US | disclosed |
| US-20210214385-A1 | INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214385-A1 | INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF | DAO, DDO, DDC | SERPINE1 1124/4885POLB 1656/4885POLA1 1865/4885 |
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | HRH4, OR10J3, CYP3A5 | SERPINE1 2936/4885POLB 4471/4885POLA1 4203/4885 |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | HRH4, OR10J3, CYP3A5 | SERPINE1 2936/4885POLB 4471/4885POLA1 4203/4885 |
| US-20240180945-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | HRH4, OR10J3, CYP3A5 | SERPINE1 2936/4885POLB 4471/4885POLA1 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.