Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23632214 | 1.00 | RORC (0.38) | RORCPDE2AUTS2RTACR1FFAR1 | |
| SCHEMBL23632212 | 1.00 | RORC (0.38) | RORCPDE2AUTS2RTACR1FFAR1 | |
| SCHEMBL23632086 | 0.92 | RORC (0.36) | RORC | |
| SCHEMBL23642247 | 0.89 | RORC (0.35) | RORCTACR1 | |
| SCHEMBL28624258 | 0.87 | RORC (0.37) | RORCPDE2ATACR1FFAR1 | |
| SCHEMBL28624256 | 0.87 | RORC (0.37) | RORCPDE2ATACR1FFAR1 | |
| SCHEMBL28609533 | 0.87 | HDAC3 (0.36) | RORCPDE2A | |
| SCHEMBL28609531 | 0.87 | HDAC3 (0.36) | RORCPDE2A | |
| SCHEMBL28916006 | 0.85 | RORC (0.46) | RORC | |
| SCHEMBL28916004 | 0.85 | RORC (0.46) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072542-B | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2021139595-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |
| CN-113072542-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |