Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | GCG | P01275 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23632833 | 1.00 | PRKAA2 (0.41) | PRKAA2ACACBEPHX2GRM4TACR1 | |
| SCHEMBL28592571 | 0.92 | ACACB (0.41) | PRKAA2ACACBGRM4TACR1TACR3 | |
| SCHEMBL30065111 | 0.92 | ACACB (0.41) | PRKAA2ACACBGRM4TACR1TACR3 | |
| SCHEMBL23632467 | 0.91 | PRKAA2 (0.42) | PRKAA2ACACBEPHX2GRM4TACR1 | |
| SCHEMBL23632822 | 0.90 | ACACB (0.37) | PRKAA2ACACBEPHX2GRM4LIPG | |
| SCHEMBL23632578 | 0.90 | ACACB (0.37) | PRKAA2ACACBEPHX2GRM4LIPG | |
| SCHEMBL23632613 | 0.87 | EPHX2 (0.42) | EPHX2LIPGADRB2LTA4H | |
| SCHEMBL23632256 | 0.87 | EPHX2 (0.42) | EPHX2LIPGADRB2LTA4H | |
| SCHEMBL23632629 | 0.86 | PRKAA2 (0.41) | PRKAA2ACACBEPHX2GRM4TACR1 | |
| SCHEMBL23632193 | 0.86 | PRKAA2 (0.41) | PRKAA2ACACBEPHX2GRM4TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |