Sugi Predict

Sugi Predict / Compounds / Phosphine

Phosphine

Phosphine

SCHEMBL23633149

P.c1ccc2c(c1)-c1ccccc1C21c2ccccc2-c2ccc(Oc3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)cc21

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 16/20 0.53
▸ MAOA P21397 3/20 0.41
▸ MAOB P27338 3/20 0.41
▸ KDM4E B2RXH2 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ OPRK1 P41145 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26580911 0.88 PDK2 (0.54) PDK2MAOAMAOBMEN1LMNA
SCHEMBL23372004 0.81 PDK2 (0.41) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL30672129 0.78 PDK2 (0.42) PDK2
SCHEMBL19862734 0.78 PDK2 (0.42) PDK2
SCHEMBL29137464 0.78 PDK2 (0.42) PDK2
SCHEMBL6854533 0.77 PDK2 (0.47) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL6854806 0.77 PDK2 (0.47) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL6854556 0.77 PDK2 (0.47) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL20198347 0.75 PDK2 (0.37) PDK2
SCHEMBL806884 0.75 PDK2 (0.68) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141428-A1 BISANTHRACENE DERIVATIVES HAVING SOLUBILIZING SUBSTITUENT, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 엘지화학 2021-07-15 — — WO disclosed