Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 17/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854533 | 1.00 | PDK2 (0.47) | PDK2THRBTDP1MEN1USP2 | |
| SCHEMBL6854806 | 1.00 | PDK2 (0.47) | PDK2THRBTDP1MEN1USP2 | |
| SCHEMBL6859729 | 0.91 | PDK2 (0.39) | PDK2TDP1MEN1USP2ALDH1A1 | |
| SCHEMBL1355713 | 0.89 | MAPT (0.51) | PDK2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL1116239 | 0.85 | PDK2 (0.46) | PDK2THRBTDP1 | |
| SCHEMBL1116178 | 0.85 | KMT2A (0.50) | PDK2MEN1KMT2A | |
| SCHEMBL29182587 | 0.78 | PDK2 (0.43) | PDK2THRBTDP1MEN1LMNA | |
| Phosphine SCHEMBL23633149 | 0.77 | PDK2 (0.53) | PDK2MEN1LMNAMAPTKMT2A | |
| SCHEMBL7810593 | 0.76 | KDM4E (0.36) | PDK2MAPT | |
| SCHEMBL4853061 | 0.76 | MAPT (0.45) | PDK2THRBTDP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935691-B1 | OPTICAL BRIGHTENING AGENT | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-05-26 | — | — | EP | disclosed |
| EP-0676461-B1 | Spiro compounds and their application as electroluminescence materials | COVION ORGANIC SEMICONDUCTORS (DE) | 2002-08-14 | — | — | EP | disclosed |
| EP-0968175-B1 | SPIRO COMPOUNDS AND THE USE THEREOF | CELANESE VENTURES GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| EP-0968175-A1 | SPIRO COMPOUNDS AND THE USE THEREOF | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-01-05 | — | — | EP | disclosed |
| EP-0935691-A1 | OPTICAL BRIGHTENING AGENT | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998042655-A1 | SPIRO COMPOUNDS AND THE USE THEREOF | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998018996-A1 | OPTICAL BRIGHTENING AGENT | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-05-07 | — | — | WO | disclosed |
| EP-0676461-A2 | Spiro compounds and their application as electroluminescence materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |